Indian Journal of Public Health Research & Development

Shruthi Parthasarathy ¹, Sarumathi Thirugnanamurthy ¹, A. Amudhan ¹, V. T. Hemalatha ¹, T. Manigandan ¹

Affiliations
1 Department of Oral Medicine and Radiology, Sree Balaji Dental College and Hospital BIHER, Chennai, IN

Abstract

The prescription of antibiotics is reaching its peak day by day in all specialities. This is causing antibiotic resistance in many bacteria along with evolution of newer multiple drug resistant strains of bacteria. If this situation continues then we would tend to ‘lose battle against the bugs’. Dentistry is a speciality commonly prescribing antibiotics all over the world. Lack of proper knowledge and lethargic attitude of many dentists contribute largely to the increasing antibiotic resistance among patients.

Keywords

Antibiotics, Bacterial Resistance, Dentistry.

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R. Bhargavi ¹, V. T. Hemalatha ¹, A. Amudhan ², T. Sarumathi , T. Manigandan

Affiliations
1 Sree Balaji Dental College and Hospital, BIHER, Chennai, Tamil Nadu, IN
2 Department of Oral Medicine and Radiology, Sree Balaji Dental College and Hospital, BIHER, Chennai, Tamil Nadu, IN

Abstract

Being the most common medical professionals in prescribing of Non-steroidal anti- inflammatory medications, Dentist in India are to be essentially aware of banned medications, that due to various reasons, still haven’t been withdrawn from market. Many fixed drug combinations are easily available without any scientific justification behind them. This article aims in creating an awareness among the dentist regarding banned fixed drug combinations of NSAIDS in India since September 2018.

Keywords

Banned drugs, NSAIDs, Fixed Drug Combinations. Corresponding Author:

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S. Angelinteena ¹, Nalini Aswath ¹, V. T. Hemalatha ¹, A. AMUDHAN ², T. Sarumathi ²

Affiliations
1 Sree Balaji Dental College and Hospital, BIHER, Chennai, Tamil Nadu, IN
2 Department of Oral Medicine and Radiology, Sree Balaji Dental College and Hospital, BIHER, Chennai, Tamil Nadu, IN

Abstract

Anaphylaxis is a severe, life-threatening, generalized or systemic hypersensitivity condition with increased mortality and requires immediate management. Dentist will face this kind of risky entity most commonly while administering local anesthesia. This review is just to update and to impart knowledge regarding management of anaphylaxis to the dentists to avoid fatality.

Keywords

Anaphylaxis, Dentistry, Adrenaline, Lignocaine.

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H. Aravindhswamy ¹, R. Sankar Narayanan ¹, T. Manigandan ¹, Nalini Aswath ¹, V. T. Hemalatha ²

Affiliations
1 Sree Balaji Dental College and Hospital, BIHER, Chennai, Tamil Nadu, IN
2 Department of Oral Medicine and Radiology, Sree Balaji Dental College and Hospital, BIHER, Chennai, Tamil Nadu, IN

Abstract

Pharmacovigilance is useful toreassure the safety of drugs and protecting the consumers from their injuries effects. A number of single drugs as well as fixed dose combinations have been banned from manufacturing, marketing and distribution in India. An important issue about the availability of banned drugs over the counter in India is that sufficient adverse drug reactions data about these drugs have not been reported. The most common categories of drugs withdrawn in the last decade were non steroidal anti inflammatory drugs (28%), antidiabetics (14.28%), antiobesity (14.28%), antihistamines (14.28%), gastroprokinetic drugs (7.14%), breast cancer and infertility drugs (7.14%), irritable bowel syndrome and constipation drugs (7.14%) and antibiotics (7.14%). Drug withdrawals from market were made mainly due to safety issues involving cardiovascular events (57.14%), liver damage (14.28%), and carcinogenic reasons . Majority of drugs have been banned since 3-5 years in other countries but are still available for sale in India. The present study says about how to manage adverse drug reactions and to prevent it in advance and provides implications for developing a system that can ensure the safety and efficacy of drugs in India.There should be a multidisciplinary approach towards drug safety that should be implemented throughout the entire duration spanning from drug discovery to usage by consumers.

Keywords

Pharmacovigilance, Adverse Drug Reaction, Drug Safety, Multidisciplinary Approach.

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Manigandan Thiruppathy ¹, D. Pavani ², A. Amudhan ¹, T. A. Sarumathi ¹, V. T. Hemalatha ³

Affiliations
1 Department of Oral Medicine and Radiology, Sree Balaji Dental College and Hospital, BIHER, Pallikaranai, IN
2 Department of Conservative Dentistry and Endodontics, Sathyabama Dental College and Hospital, Semmanchery, IN
3 Department of Oral Medicine and Radiology, Sree Balaji Dental College and Hospital, BIHER, Pallikaranai, Chennai, Tamil Nadu 600100, IN

Abstract

Dentists come across various medically compromised patients. Patients who are under anticoagulant and/ or antiplatelet drugs should be taken into consideration as they are at a high risk to have increased bleeding tendency during minor oral surgical procedures. The substances, which prevent or prolong coagulation of blood, are called Anticoagulants1. The most commonly used medications for oral anticoagulant therapy are Warfarin, Acenocoumarol. The novel oral anticoagulants (NOACs) or directly acting oral anticoagulants [DOACs] were developed with more pharmacokinetic and pharmacodynamic relationships, faster onset of action, and fewer potential interactions. The Novel anticoagulants include Dabigatran Rivaroxaban, Apixaban, Edoxaban.

Keywords

Novel Anticoagulants, Dabigatran, Apixaban.

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V. T. Hemalatha ¹, Melody Khwairakpam ², R. Sankar Narayanan ², A. Amudhan ³

Affiliations
1 Department of Oral Medicine and Radiology, Sree Balaji Dental College and Hospital, BIHER Chennai–100, IN
2 Sree Balaji Dental College and Hospital, IN
3 Department of Oral Medicine and Radiology, Sree Balaji Dental College and Hospital, IN

Abstract

Keratocystic odontogenic tumors (KCOTs) are called for their disputed peculiar characteristics, varied origin, unique propensity to recur, disputed treatment methods and can occur anywhere in the jaw, but mainly seen in the posterior part of the mandible. On radiographically, it present, as well-defined radiolucent lesions with smooth and generally corticated margins. They are benign intraosseous tumors of odontogenic origin that occur most mainly in the jaw. The average reported recurrence rate ranges from 30 to 62 present.

Keywords

Keratocyst, Odontogenic, Molar, Ramus.

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